Articoli scientifici

Metallic taste: an unusual reaction to botulinum toxin A

Murray C, Solish N.
University of Toronto, Toronto, Ontario, Canada.


BACKGROUND: Botulinum neurotoxin formulations are safe and effective agents for the treatment of facial rhytides.

OBJECTIVES: A patient is described who complained of metallic taste after each treatment with botulinum toxin A (BTX-A).

RESULTS: The sensation of metallic taste diminished after successive treatments with BTX-A, despite adequate dosing for cosmetic purposes.

CONCLUSION: Metallic taste is associated with the use of numerous medications; however, the pathogenesis remains unclear. Alteration in zinc metabolism, which may occur with BTX-A administration, has been suggested as a possible mechanism. Although this is the first known report of dysgeusia after BTX-A, physicians and patients may be reassured that the taste alteration was self-limited and was not significantly problematic for the patient in our case.